Rare Disease Biotech Offers Access Ahead of Key Milestone

This late-stage biotech is gearing up for Phase 2 trials with an FDA-designated orphan drug. It's already drawing comparisons to recent billion-dollar exits. Backed by a proven biotech incubator, it's now offering early access to its raise.

What You Need to Know About Annuities

Christine Benz & Margaret Giles of Morningstar
October 01, 2025

Retirement researchers are often enthusiastic about annuities, but many consumers are reasonably skeptical. Here to discuss basic information about annuities and their pros and cons is Christine Benz, Morningstar's director of personal finance and retirement planning.

This interview has been edited for length and clarity.

Q: How do income annuities work, and how they are different from investing in something that pays out income like bonds?

A: An annuity is a contract with an insurance company. In the most basic annuity type, income annuities, you give the insurance company a pool of your money, and they send it back to you as a stream of income over your lifetime. Those types of products give you more income than you could earn by investing in a bond.

They do that because you benefit in the annuity by what's called "longevity risk pooling," which means that some people who are buying that same annuity will die sooner, which enlarges the payout for the whole group of you. If you're the one who lives to be 99, you're the winner in that situation. That's one reason that payouts are higher than you'd see for traditional fixed-income instruments. The other big reason is that if you buy an annuity, your money is gone, effectively. You get cash flows, but you can't get your principal back. In contrast, when you buy a bond, you receive income, but you receive your principal back at the end.

Q: How can these types of annuities help with retirement planning?

A: These very basic income annuities can be helpful in terms of addressing a household's basic living expenses. Say my household basic expenses--housing, taxes, healthcare--total $40,000, and Social Security is going to give me another $30,000 of that $40,000. I could buy an annuity that will supply me with $10,000 a year to help meet those basic cash flow needs. That's an elegant use of an annuity, and it can help retirees figure out how much they would want to put into such a product, by examining how much they actually need from it.

Q: Savings annuities, or "deferred annuities," allow investors to get market exposure in addition to income. What are some key savings annuity types?

A: The most familiar one is a variable annuity where you're in control of the investment allocations. There are also increasingly popular "fixed index" annuities, where you get market exposure, but there are caps on your gains. There are also caps on your losses. Registered index-linked annuities fall between those two product types on the risk spectrum.

Q: These products are more complicated than income annuities, and they carry more risk and higher costs. How can investors make sure they know what they're getting into with these products?

A: Typically, these products carry really long contracts with lots of fine print. That can be very difficult for consumers to wade through. You can hire an objective third party to help you understand what you might be getting into.

At a minimum, write down all of your questions. There are no stupid questions in this context, because transparency isn't there for consumers. Ask about costs, withdrawals, and what you're getting with this product that you couldn't get with a very vanilla investment portfolio that would also give you more liquidity and more access to your funds. Until you have exhausted all of those questions, don't sign on the bottom line. You also want to ask about the financial strength of the insurance company backing the annuity, because this is a long-term relationship. You need to make sure that they're able to make good on whatever promises they're making.

Q: What are the tax implications of annuities?

A: It depends on the account that you use to fund the annuity, but generally, you will owe taxes. You get some tax deferral as long as the funds are in the annuity, and then you'll owe taxes on any money that hasn't been taxed yet. If you put pretax dollars into an annuity and it makes investment gains, all of your withdrawals will be taxable at your ordinary income tax rate.

_____

This article was provided to The Associated Press by Morningstar. For more personal finance content, go to https://www.morningstar.com/personal-finance

Christine Benz is Morningstar's director of personal finance and retirement planning.

Related links:

Continue Reading...

Popular

FBI Director Kash Patel Bought 2 Stocks In 2025 — One's Already A Meme Favorite

FBI Director Kash Patel was asked about two stocks he bought earlier this year by a member of Congress on Wednesday and gave a surprising answer. The transactions come as members of Congress are working on legislation to ban lawmakers and cabinet members from buying and selling stocks.

Here's How Much $1000 Invested In Union Pacific 20 Years Ago Would Be Worth Today

Union Pacific (NYSE: UNP) has outperformed the market over the past 20 years by 4.88% on an annualized basis producing an average annual return of 13.7%. Currently, Union Pacific has a market capitalization of $138.27 billion.

New Biotech Offering Targets $426B Rare Disease Market - Ad

The rare disease drug space is growing fast-and so is investor interest. With exclusivity, pricing power and major M&A moves, the rare disease space is getting interesting. This company has the science and the experience.

America Has A New No. 1 Beer — And It's Got Bud Light DNA

When it comes to beer in the United States, there's a new bestselling brand.

Enanta's RSV Pill Shows Promise In Cutting Recovery Time For High-Risk Adults

Enanta Pharmaceuticals, Inc. (NASDAQ: ENTA) on Monday released topline data from RSVHR Phase 2b study of zelicapavir in outpatient adults with acute respiratory syncytial virus (RSV) infection who are at high risk of complications, including the elderly and/or those with congestive heart failure (CHF), chro

[Revealed] Trump's Next AI Executive Orders? - Ad

A White House insider with direct ties to Trump's inner circle just revealed what he calls "Manhattan II" - a potential $2.2 trillion AI initiative set to launch as soon as Oct 15. He says this could mirror past U.S. projects that minted fortunes - with small firms soaring 5,000% to 10,000% over two decades. And now he's giving away his #1 stock pick for free before the deadline.

Ex-Trump Lawyer Raises Alarms: 'I Have Never Been As Concerned As To Whether Our System Can Withstand The Pressure'

Abbe Lowell, a lawyer who once represented President Donald Trump's family, has expressed grave concerns over the potential harm the current administration could cause to the country's institutions.

The "Mar-A-Lago Accord" Is Now Underway - Ad

The global order is in chaos. And according to 40-year market veteran Dr. David Eifrig, the biggest controlled demolition of the old monetary order in history could now be here, too. That means if you don't take action today, your wealth could decline by 40%... (Yes, even your cash savings.)

BlackRock Turns Popular Mutual Funds Into Global Equity ETFs

BlackRock turns two top mutual funds into active ETFs, giving investors global equity exposure and strategies to manage volatility.

IBM Stock Jumps 5% After Quantum Computing Breakthrough

Shares of International Business Machines Corporation (NASDAQ: IBM) are up Thursday after the company announced it reached a technological milestone in quantum computin

Gold Is Being Reintroduced Into the Monetary System - Ad

While the media focuses on political scandals, inflation and coming up with ridiculous acronyms "TACO"... Smart money is tracking a far bigger shift: a gold revaluation is quietly underway. Garrett Goggin, CFA, says this could trigger 100X moves in select miners - and he's identified four with the biggest upside.

Day of strikes in France challenges new prime minister's budget plans

PARIS (AP) — Strikes and street demonstrations called by all major trade unions to denounce budget cuts were expected Thursday across France, as new talks with political opponents about curbing .

TikTok Stays Online As Trump Extends US Deadline, Washington Still Demands ByteDance Divestment

President Trump said he and Chinese President Xi Jinping made progress on a TikTok deal and will meet in South Korea in just over a month.

The Tesla Shock Nobody Sees Coming - Ad

While headlines scream "Tesla is doomed"...Jeff Brown has uncovered a revolutionary AI breakthrough buried inside Tesla's labs. One that is helping AI escape from our computer screens and manifest itself here in the real world all while creating a 25,000% growth market explosion starting as early as October 23rd.

Tesla Faces Class Action Over 'Wage Theft' Amid Preference For H-1B Workers Following Elon Musk's Push To Optimize Visa Practice

Tesla is facing a federal class action lawsuit accusing it of favoring H-1B visa holders over U.S. workers to cut labor costs, even as the company battles financial headwinds and regulatory scrutiny.

Kevin O'Leary Once Admitted He Wasn't The Best Dad — But The Shark Gave Himself A '10 Out Of 10' Score In One Key Area

Kevin O'Leary admitted he wasn't always present as a father but said financial stability made him a "10 out of 10" provider, sharing how tough-love lessons with his son and sacrifices echoed by Barack Obama and Mark Cuban highlight the trade-offs between family and success.

Biotech With Multiple Orphan Drugs Is Quietly Opening Its Doors - Ad

A promising biotech developing treatments for rare childhood brain diseases is opening a new raise. Its lead drug has fast-track status, orphan designations, is nearing Phase 2 and backed by a Global Integrator.

Johnson & Johnson's Tecvayli-Darzalex Combo Shows 100% Response In Newly Diagnosed Myeloma Patients

Johnson & Johnson's Tecvayli-Darzalex regimen showed 100% response rates and high MRD negativity in newly diagnosed multiple myeloma patients.

Jerome Powell and Economists Agree: Gen Z Faces a Hiring Crisis And That's Not About AI

In 2025, the rising unemployment rate among Americans under 25, specifically recent graduates, has become a significant economic concern.

Why This Crypto Skeptic Had a Change of Heart - Ad

He used to make fun of crypto. Now... he says one $3 crypto could rise to $92 by next year.

Charlie Kirk Raised $85 Million Last Year — Widow Vows to Continue His Work

The assassination of Turning Point USA founder Charlie Kirk at a Utah Valley University event on September 10 has cast a shadow of uncertainty over the future of his political and business ventures.

Time to Say Goodbye to "Old" Dollar? Say Hello to "Trump's New Dollar" - Ad

If you have any money in U.S. dollars... learn how to prepare for "Trump's new dollar"... Because this could be the biggest change to our financial system in 54 years. President Trump even called it: "The greatest revolution in financial technology since the birth of the internet itself."

NYC mayor throws support behind bill to ban Central Park horse carriages

NEW YORK (AP) — New York City’s mayor threw his support Wednesday behind a proposal to that have been fixtures in Central Park for more than 150 years as he ordered police to more stringently enforce laws already on the books to rein in the industry.

UK inflation remains nearly double target ahead of expected interest rate hold

LONDON (AP) — Inflation in the U.K. held steady at 3.8% in the year to August, official figures showed Wednesday, a day before the Bank of England is widely expected to keep interest rates on hold.

Elon's $25 Trillion Confession - Ad

Elon Musk: "Tesla will become a $25 trillion company." That would make Tesla 8x bigger than Apple today. How is that possible? He admits it's all thanks to this one AI breakthrough that will take AI out of our computer screens and manifest a 250x boom here in the real world.

Trump's Immigration Policies Could 'Shrink' GDP Growth As US Population Projected To Decline, Warns CBO

The U.S. population growth is expected to decline at a faster rate than previously projected due to President Donald Trump's immigration policies, according to the Congressional Budget Office (CBO).

Qatar denounces Israel before major summit on Israel's attack in Doha targeting Hamas leaders

DUBAI, United Arab Emirates (AP) — Qatar's prime minister denounced Israel on Sunday as foreign ministers from Arab and Muslim nations met to discuss a possible unified targeting the leadership of the militant group Hamas.

Rare Disease Biotech Offers Access Ahead of Key Milestone - Ad

This late-stage biotech is gearing up for Phase 2 trials with an FDA-designated orphan drug. It's already drawing comparisons to recent billion-dollar exits. Backed by a proven biotech incubator, it's now offering early access to its raise.

Carney Cuts The Red Tape, Unveils Over $43 Billion In Flagship Projects

PM Mark Carney announces first projects to be reviewed by Canada's new Major Projects Office, aiming to cut red tape and attract investments.

Three-Chart Case For Silver's Outperformance

Silver may be entering a new bull phase, supported by the gold-to-silver ratio, its ratio to the S&P 500, and a major long-term technical breakout.

New Biotech Offering Targets $426B Rare Disease Market - Ad

The rare disease drug space is growing fast-and so is investor interest. With exclusivity, pricing power and major M&A moves, the rare disease space is getting interesting. This company has the science and the experience.

Gen Z's credit scores are dropping. Here's what to do if yours is too

NEW YORK (AP) — Gen Z has seen its drop more than any other generation over the past year, largely because of student loan debt, according to a new report out this week.

Bitcoin Gets The Jitters Around $115,000: Up Or Down Ahead Of FOMC Day?

Bitcoin's (CRYPTO: BTC) tapped $116,000 before retracing below $115,000 on Monday, signaling that fresh catalysts may be needed to lift sentiment as weakening metrics signal a potential pullback.

[Revealed] Trump's Next AI Executive Orders? - Ad

A White House insider with direct ties to Trump's inner circle just revealed what he calls "Manhattan II" - a potential $2.2 trillion AI initiative set to launch as soon as Oct 15. He says this could mirror past U.S. projects that minted fortunes - with small firms soaring 5,000% to 10,000% over two decades. And now he's giving away his #1 stock pick for free before the deadline.

The late Italian fashion designer Giorgio Armani instructs heirs to sell 15% of his empire

MILAN (AP) — After a lifetime of spurning would-be business suitors, the late Italian designer instructed his heirs to sell a 15% minority stake in his vast fashion empire, with priority to the French conglomerate LVMH, the eyewear giant Essilor-Luxottica or the cosmetics company L’Oreal.

The "Mar-A-Lago Accord" Is Now Underway - Ad

The global order is in chaos. And according to 40-year market veteran Dr. David Eifrig, the biggest controlled demolition of the old monetary order in history could now be here, too. That means if you don't take action today, your wealth could decline by 40%... (Yes, even your cash savings.)

'Bitcoin Bottom Day' Tomorrow Could Define Trend – Expert Predicts 70% Chance BTC Secures $100K Floor"

Bitcoin (CRYPTO: BTC) is trading near $115,000 as traders eye September 21, a date that could prove pivotal in shaping the crypto king's trajectory through the rest of 2025.

Trending Now

Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.

Copyright traderelite.club
Privacy Policy | Terms of Service